Thursday, June 21, 2012

Transient Neonatal Pustular Melanosis

TNPM is a condition marked by pustules and vesicles that are present at birth, and which heal with a collarette of scale and, eventually, a hyperpigmented macule.  It is fairly common in African American children, and is remarkable in that the pustules are loaded with neutrophils.  It differs from Erythema Toxicum Neonatorum in that it is present at birth (ETN usually has its onset after birth), has a relatively normal background (ETN has an erythematous background) and by the predominance of neuts on smear (ETN has numerous eosinophils).  Most of you nailed this one.  Good job!

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